The organisation, conception and objectives of Propylaeum are accompanied by a scientific advisory board. Together with the two operating libraries, it defines the guidelines for the operation and further development of the Specialized Information Service Ancient Studies and ensures continuous quality assurance. The research areas of the members reflect the range of subjects covered by Propylaeum.

• Dr. Kerstin P. Hofmann (Pre- and Early History, Römisch-Germanische Kommission des DAI)
• Prof. Dr. Peter von Möllendorff (Greek Philology, Justus-Liebig-Universität Gießen)
• Prof. Dr. Peter Orth (Medieval Latin Philology, Universität zu Köln)
• Prof. Dr. Diamantis Panagiotopoulos (Classical Archaeology, Ruprecht-Karls-Universität Heidelberg)
• Prof. Dr. Joachim Quack (Egyptology, Ruprecht-Karls-Universität Heidelberg)
• Prof. Dr. Walther Sallaberger (Assyriology, Ludwig-Maximilians-Universität München)
• Prof. Dr. Ulrich Schmitzer (Latin Philology, Humboldt-Universität zu Berlin)
• Prof. Dr. Charlotte Schubert (Ancient History, Universität Leipzig)
• Prof. Dr. Andreas Schwab (Classical Philology / Greek Philology, Christian-Albrechts-Universität zu Kiel)
• Prof. Dr. Martina Seifert (Classical Archaeology, Universität Hamburg)
• Prof. Dr. Gregor Weber (Ancient History, Universität Augsburg)
• N. N. (Byzantine Studies, N. N.)